Prep the Stain

• Before you proceed with using any type of leather cleaner or stain remover, you need to do some prep work. Blot up as much of the stain as you can with a white cloth. Vacuum the leather upholstery to remove dirt and debris. If you don't do this before cleaning, you may cause further staining.
  
  

Select a Cleaner

• Numerous companies make leather cleaner for car upholstery. You can use a commercial cleaner, or you can mix one up on your own. Put one cup of distilled white vinegar and two cups of linseed oil in an empty spray bottle. Shake well before each use. Spray the cleaner onto a clean white cloth and blot up stain.
  
  

Remove Mold and Mildew

• Mold and mildew stains may require special treatment above and beyond a standard cleaning solution. Mix one cup of rubbing alcohol with one cup of water in a spray bottle. Shake well, and spray onto a cloth. Blot the stain with the cleaner until it is gone. Allow the stain to air dry in the sun.
  
  

Miscellaneous Stains

• There are certain types of stains that may not come clean with a standard leather cleaner. Ink, markers and certain foods are examples of this. Hairspray, toothpaste and non-acetone nail polish remover can lift tough stains. Apply the stain remover to the stain, blot it up and repeat the process until the stain is gone.